MDRO’s

Posted By Chris on April 26, 2011

The CDC defines Multidrug-resistant Organisms (MDRO’s) as microorganisms that have developed resistance to multiple antimicrobial drugs; two MDRO’s we are most familiar with in Long-term Care are MRSA (Methicillin -resistant Staphylococcus aureus) and VRE (Vancomycin-resistant Enterococcus). Patients, health-care workers and visitors are potential sources of MDRO’s. They may be colonized, infected, and unknowingly transmitting resistant organisms to one another.

Colonization is defined as the presence of an organism in or on the body but with no clinical signs and symptoms of infection. Infection is defined as tissue invasion by a microorganism accompanied by positive clinical signs and symptoms.

Since health care workers, patients and family alike are often unaware they are colonized with Multi-Drug Resistant Organisms, it follows they could easily be transmitted from one person to another. Inadequate hand hygiene is the root cause for transmission of pathogens in Long-Term Care and in all other health care settings as well. Health care workers, patients and visitors must do all they can to interrupt the cycle of transmission by consciously and conscientiously washing their hands. 

Multi-drug Resistant organisms are not necessarily more virulent than their non-resistant predecessors but resistance contributes to fewer treatment options with antimicrobials.  Reducing exposure to MDRO’s is accomplished by using the same approach to preventing transmission of all pathogens found in health care facilities;  Standard Precautions.

Use Standard Precautions at all times for all patients. Intensify interventions when the Condition That Facilitates Transmission cannot be contained. 

Always practice responsible Hand Hygiene

PPE (Personal Protective Equipment) use gloves, gowns and masks appropriately. Give frequent demonstrations on the correct procedures for donning, removing and disposing of PPE, followed by staff return demonstrations.  CDC Donning and Removing PPE see illustrations on page 134 & 135 of the CDC 2007 Isolation Guidelines.

Optimize Room Placement of patients with known infections; co-hort those with like infectious organisms.  

Assess patients for group activities. In general, if a patient’s wounds are covered and contained, if they are not exhibiting clinical signs and symptoms of infection, and if they are able to demonstrate responsible hygiene practices, it is usually acceptable for them to socialize and participate in activities.  Check the Policies & Procedures for your facility.

Conversely, if wounds cannot be covered and drainage contained, if the patient is confused or unable to engage in good hygiene practices, if they demonstrate clinical signs of infection such as fever, active vomiting/diarrhea or if they are coughing productively, activities should be limited until signs and symptoms have subsided. Again, review and educate your staff to your facility Policy & Procedures, which should be updated as needed for federal, state and local Standards of Care and Best Practice Guidelines.

About the author

Chris

Hello, my name is Chris Walter. I am a Registered Nurse with experience in several nursing specialties including Surgery, Case Management, Legal Nurse Consulting, Community Health, and Infection Prevention and Control. I have a BSN and a Public Health Nursing Certificate (PHN) in the stateof California. My hope is to facilitate the sharing of knowledge and resources with Health Care Workers who have an interest in the specialty of Infection Prevention and Control in Long-term Care. Please feel comfortable contacting me at icpreventionist@aol.com and share your comments with The Preventionist as well. I consider myself a perpetual student, rather than an expert. My intent is to provide information based on recommendations from the masters of infection control and prevention such as; • The Association for Professionals in Infection Control and Epidemiology (A.P.I.C.) • The Centers for Disease Control and Prevention (CDC) • State Department of Public Health All information contained within The Preventionist site is strictly for informational purposes only. None of the statements on this site are to be considered a recommendation for treatment of any particular disease or health related condition.

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